Description：

UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets.

Chemical Information：

Molecular Weight (MW)		569.74
Formula		C33H43N7O2
CAS No.		1431612-23-5
Solubility (25°C) *	DMSO	50 mg/mL (87.75 mM)
	Water	Insoluble
	Alcohol	50 mg/mL (87.75 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7552 mL	8.7759 mL	17.5519 mL
5 mM	0.3510 mL	1.7552 mL	3.5104 mL
10 mM	0.1755 mL	0.8776 mL	1.7552 mL
50 mM	0.0351 mL	0.1755 mL	0.3510 mL

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