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Description:
U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059.
Chemical Information:
Molecular Weight (MW) 426.56 Formula
C18H16N6S2.C2H6O
CAS No. 1173097-76-1 Solubility (25°C) * DMSO 85 mg/mL warmed (199.26 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3443 mL 11.7217 mL 23.4434 mL 5 mM 0.4689 mL 2.3443 mL 4.6887 mL 10 mM 0.2344 mL 1.1722 mL 2.3443 mL 50 mM 0.0469 mL 0.2344 mL 0.4689 mL
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