Description：

AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM in a cell-free assay. It is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck. Phase 1.

Chemical Information：

Molecular Weight (MW)		362.42
Formula		C17H19FN4O2S
CAS No.		860352-01-8
Solubility (25°C) *	DMSO	50 mg/mL (137.96 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Aminopeptidase N LAP PuSA 220 nM 100 nM 150 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7592 mL	13.7961 mL	27.5923 mL
5 mM	0.5518 mL	2.7592 mL	5.5185 mL
10 mM	0.2759 mL	1.3796 mL	2.7592 mL
50 mM	0.0552 mL	0.2759 mL	0.5518 mL

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