Description：

Triciribine is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		320.3
Formula		C13H16N6O4
CAS No.		35943-35-2
Solubility (25°C) *	DMSO	64 mg/mL (199.81 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1221 mL	15.6104 mL	31.2207 mL
5 mM	0.6244 mL	3.1221 mL	6.2441 mL
10 mM	0.3122 mL	1.5610 mL	3.1221 mL
50 mM	0.0624 mL	0.3122 mL	0.6244 mL

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