Description：

Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

Chemical Information：

Molecular Weight (MW)		615.39
Formula		C26H23FIN5O4
CAS No.		871700-17-3
Solubility (25°C) *	DMSO	22 mg/mL warmed (35.74 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6250 mL	8.1249 mL	16.2499 mL
5 mM	0.3250 mL	1.6250 mL	3.2500 mL
10 mM	0.1625 mL	0.8125 mL	1.6250 mL
50 mM	0.0325 mL	0.1625 mL	0.3250 mL

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