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Description:
TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1.
Chemical Information:
Molecular Weight (MW) 279.29 Formula
C12H10FN3O2S
CAS No. 507475-17-4 Solubility (25°C) * DMSO 56 mg/mL (200.5 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.5805 mL 17.9025 mL 35.8051 mL 5 mM 0.7161 mL 3.5805 mL 7.1610 mL 10 mM 0.3581 mL 1.7903 mL 3.5805 mL 50 mM 0.0716 mL 0.3581 mL 0.7161 mL
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