Description：

Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		457.91
Formula		C23H23N3O5.HCl
CAS No.		119413-54-6
Solubility (25°C) *	DMSO	91 mg/mL (198.72 mM)
	Water	91 mg/mL (198.72 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1838 mL	10.9192 mL	21.8384 mL
5 mM	0.4368 mL	2.1838 mL	4.3677 mL
10 mM	0.2184 mL	1.0919 mL	2.1838 mL
50 mM	0.0437 mL	0.2184 mL	0.4368 mL

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