Description：

AZD5438 is a potent inhibitor of CDK1/2/9 with IC50 of 16 nM/6 nM/20 nM in cell-free assays. It is less potent to CDK5/6 and also inhibits GSK3β. Phase 1.

Chemical Information：

Molecular Weight (MW)		371.46
Formula		C18H21N5O2S
CAS No.		602306-29-6
Solubility (25°C) *	DMSO	74 mg/mL (199.21 mM)
	Water	Insoluble
	Alcohol	74 mg/mL (199.21 mM)

Biological Activity：

Targets IC50

AT1 1.3 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6921 mL	13.4604 mL	26.9208 mL
5 mM	0.5384 mL	2.6921 mL	5.3842 mL
10 mM	0.2692 mL	1.3460 mL	2.6921 mL
50 mM	0.0538 mL	0.2692 mL	0.5384 mL

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