Description：

Tipifarnib (R115777) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.

Chemical Information：

Molecular Weight (MW)		489.4
Formula		C27H22Cl2N4O
CAS No.		192185-72-1
Solubility (25°C) *	DMSO	14 mg/mL (28.6 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0433 mL	10.2166 mL	20.4332 mL
5 mM	0.4087 mL	2.0433 mL	4.0866 mL
10 mM	0.2043 mL	1.0217 mL	2.0433 mL
50 mM	0.0409 mL	0.2043 mL	0.4087 mL

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