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Description:
Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.
Chemical Information:
Molecular Weight (MW) 334.39 Formula
C19H14N2O2S
CAS No. 865854-05-3 Solubility (25°C) * DMSO 8 mg/mL warmed (23.92 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.9905 mL 14.9526 mL 29.9052 mL 5 mM 0.5981 mL 2.9905 mL 5.9810 mL 10 mM 0.2991 mL 1.4953 mL 2.9905 mL 50 mM 0.0598 mL 0.2991 mL 0.5981 mL
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