Description：

THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7.

Chemical Information：

Molecular Weight (MW)		638.97
Formula		C31H30Cl3N7O2
CAS No.		1604810-83-4(free base)
Solubility (25°C) *	DMSO	100 mg/mL (156.5 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5650 mL	7.8251 mL	15.6502 mL
5 mM	0.3130 mL	1.5650 mL	3.1300 mL
10 mM	0.1565 mL	0.7825 mL	1.5650 mL
50 mM	0.0313 mL	0.1565 mL	0.3130 mL

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