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Description:
Tetrabenazine(Nitoman, Xenazine) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2; Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.
Chemical Information:
Molecular Weight (MW) 317.42 Formula
C19H27NO3
CAS No. 58-46-8 Solubility (25°C) * DMSO 58 mg/mL (182.72 mM) Water Insoluble Alcohol 32 mg/mL (100.81 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.1504 mL 15.7520 mL 31.5040 mL 5 mM 0.6301 mL 3.1504 mL 6.3008 mL 10 mM 0.3150 mL 1.5752 mL 3.1504 mL 50 mM 0.0630 mL 0.3150 mL 0.6301 mL
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