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Description:
Tepotinib (EMD 1214063) is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Phase 1.
Chemical Information:
Molecular Weight (MW) 492.57 Formula
C29H28N6O2
CAS No. 1100598-32-0 Solubility (25°C) * DMSO 5 mg/mL warmed (10.15 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.0302 mL 10.1508 mL 20.3017 mL 5 mM 0.4060 mL 2.0302 mL 4.0603 mL 10 mM 0.2030 mL 1.0151 mL 2.0302 mL 50 mM 0.0406 mL 0.2030 mL 0.4060 mL
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