Description：

AZD3463 is a novel orally bioavailable ALK inhibitor with K_i of 0.75 nM, which also inhibits IGF1R with equivalent potency.

Chemical Information：

Molecular Weight (MW)		448.95
Formula		C24H25ClN6O
CAS No.		1356962-20-3
Solubility (25°C) *	DMSO	24 mg/mL (53.45 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

CDK2 CDK5 CDK7 8 nM 5 nM 10 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2274 mL	11.1371 mL	22.2742 mL
5 mM	0.4455 mL	2.2274 mL	4.4548 mL
10 mM	0.2227 mL	1.1137 mL	2.2274 mL
50 mM	0.0445 mL	0.2227 mL	0.4455 mL

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