Description：

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.

Chemical Information：

Molecular Weight (MW)		453.52
Formula		C21H23N7O3S
CAS No.		486424-20-8
Solubility (25°C) *	DMSO	7 mg/mL (15.43 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

HD1-A (Maize) HD1-B (Maize) 100 nM 3400 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2050 mL	11.0249 mL	22.0497 mL
5 mM	0.4410 mL	2.2050 mL	4.4099 mL
10 mM	0.2205 mL	1.1025 mL	2.2050 mL
50 mM	0.0441 mL	0.2205 mL	0.4410 mL

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