Description：

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Phase 2.

Chemical Information：

Molecular Weight (MW)		585.69
Formula		C31H43N3O8
CAS No.		75747-14-7
Solubility (25°C) *	DMSO	100 mg/mL (170.73 mM)
	Water	Insoluble
	Alcohol	5 mg/mL (8.53 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7074 mL	8.5369 mL	17.0739 mL
5 mM	0.3415 mL	1.7074 mL	3.4148 mL
10 mM	0.1707 mL	0.8537 mL	1.7074 mL
50 mM	0.0341 mL	0.1707 mL	0.3415 mL

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