Description：

TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.

Chemical Information：

Molecular Weight (MW)		504.23
Formula		C17H15F2IN4O4
CAS No.		1035555-63-5
Solubility (25°C) *	DMSO	101 mg/mL (200.3 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9832 mL	9.9161 mL	19.8322 mL
5 mM	0.3966 mL	1.9832 mL	3.9664 mL
10 mM	0.1983 mL	0.9916 mL	1.9832 mL
50 mM	0.0397 mL	0.1983 mL	0.3966 mL

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