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Description:
TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.
Chemical Information:
Molecular Weight (MW) 399.51 Formula
C24H21N3OS
CAS No. 303162-79-0 Solubility (25°C) * DMSO 80 mg/mL (200.24 mM) Water Insoluble Alcohol 16 mg/mL (40.04 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5031 mL 12.5153 mL 25.0307 mL 5 mM 0.5006 mL 2.5031 mL 5.0061 mL 10 mM 0.2503 mL 1.2515 mL 2.5031 mL 50 mM 0.0501 mL 0.2503 mL 0.5006 mL
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