Description：

TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.

Chemical Information：

Molecular Weight (MW)		307.35
Formula		C18H17N3O2
CAS No.		426219-18-3
Solubility (25°C) *	DMSO	61 mg/mL (198.47 mM)
	Water	Insoluble
	Alcohol	8 mg/mL (26.02 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.2536 mL	16.2681 mL	32.5362 mL
5 mM	0.6507 mL	3.2536 mL	6.5072 mL
10 mM	0.3254 mL	1.6268 mL	3.2536 mL
50 mM	0.0651 mL	0.3254 mL	0.6507 mL

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