Description：

AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. Phase 2.

Chemical Information：

Molecular Weight (MW)		388.87
Formula		C19H17ClN2O3S
CAS No.		802904-66-1
Solubility (25°C) *	DMSO	11 mg/mL (28.28 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

P-glycoprotein 60 nM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5716 mL	12.8578 mL	25.7155 mL
5 mM	0.5143 mL	2.5716 mL	5.1431 mL
10 mM	0.2572 mL	1.2858 mL	2.5716 mL
50 mM	0.0514 mL	0.2572 mL	0.5143 mL

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