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Description:
TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.
Chemical Information:
Molecular Weight (MW) 468.94 Formula
C23H25ClN6O3
CAS No. 761437-28-9 Solubility (25°C) * DMSO 94 mg/mL (200.45 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1325 mL 10.6623 mL 21.3247 mL 5 mM 0.4265 mL 2.1325 mL 4.2649 mL 10 mM 0.2132 mL 1.0662 mL 2.1325 mL 50 mM 0.0426 mL 0.2132 mL 0.4265 mL
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