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TAE226 (NVP-TAE226)

TAE226 (NVP-TAE226)

Catalog Number: CC2976 Rank: comment rank 5

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Description:

TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.

Chemical Information:

Molecular Weight (MW) 468.94
Formula

 

C23H25ClN6O3

 

CAS No. 761437-28-9
Solubility (25°C) * DMSO 94 mg/mL (200.45 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1325 mL 10.6623 mL 21.3247 mL
5 mM 0.4265 mL 2.1325 mL 4.2649 mL
10 mM 0.2132 mL 1.0662 mL 2.1325 mL
50 mM 0.0426 mL 0.2132 mL 0.4265 mL


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