Description：

Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex.

Chemical Information：

Molecular Weight (MW)		804.02
Formula		C44H69NO12
CAS No.		104987-11-3
Solubility (25°C) *	DMSO	94 mg/mL (116.91 mM)
	Water	Insoluble
	Alcohol	83 mg/mL (103.23 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.2438 mL	6.2188 mL	12.4375 mL
5 mM	0.2488 mL	1.2438 mL	2.4875 mL
10 mM	0.1244 mL	0.6219 mL	1.2438 mL
50 mM	0.0249 mL	0.1244 mL	0.2488 mL

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