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Description:
STF-62247 is a molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. STF-62247 shows selective toxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).
Chemical Information:
Molecular Weight (MW) 267.35 Formula
C15H13N3S
CAS No. 315702-99-9 Solubility (25°C) * DMSO 53 mg/mL (198.24 mM) Water Insoluble Alcohol 3 mg/mL (11.22 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.7404 mL 18.7021 mL 37.4042 mL 5 mM 0.7481 mL 3.7404 mL 7.4808 mL 10 mM 0.3740 mL 1.8702 mL 3.7404 mL 50 mM 0.0748 mL 0.3740 mL 0.7481 mL
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