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STF-62247

STF-62247

Catalog Number: CC1197 Rank: comment rank 5

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Description:

STF-62247 is a molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. STF-62247 shows selective toxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).

Chemical Information:

Molecular Weight (MW) 267.35
Formula

 

C15H13N3S

 

CAS No. 315702-99-9
Solubility (25°C) * DMSO 53 mg/mL (198.24 mM)
Water Insoluble
Alcohol 3 mg/mL (11.22 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.7404 mL 18.7021 mL 37.4042 mL
5 mM 0.7481 mL 3.7404 mL 7.4808 mL
10 mM 0.3740 mL 1.8702 mL 3.7404 mL
50 mM 0.0748 mL 0.3740 mL 0.7481 mL


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