Description：

Sotrastaurin is a potent and selective pan-PKC inhibitor, mostly for PKCθ with K_i of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.

Chemical Information：

Molecular Weight (MW)		438.48
Formula		C25H22N6O2
CAS No.		425637-18-9
Solubility (25°C) *	DMSO	87 mg/mL (198.41 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (4.56 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2806 mL	11.4030 mL	22.8061 mL
5 mM	0.4561 mL	2.2806 mL	4.5612 mL
10 mM	0.2281 mL	1.1403 mL	2.2806 mL
50 mM	0.0456 mL	0.2281 mL	0.4561 mL

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