Description：

Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		464.82
Formula		C21H16ClF3N4O3
CAS No.		284461-73-0
Solubility (25°C) *	DMSO	63 mg/mL warmed (135.53 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1514 mL	10.7569 mL	21.5137 mL
5 mM	0.4303 mL	2.1514 mL	4.3027 mL
10 mM	0.2151 mL	1.0757 mL	2.1514 mL
50 mM	0.0430 mL	0.2151 mL	0.4303 mL

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