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Description:
SNX-2112 (PF-04928473) selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG.
Chemical Information:
Molecular Weight (MW) 464.48 Formula
C23H27F3N4O3
CAS No. 908112-43-6 Solubility (25°C) * DMSO 93 mg/mL (200.22 mM) Water Insoluble Alcohol 1 mg/mL (2.15 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1529 mL 10.7647 mL 21.5295 mL 5 mM 0.4306 mL 2.1529 mL 4.3059 mL 10 mM 0.2153 mL 1.0765 mL 2.1529 mL 50 mM 0.0431 mL 0.2153 mL 0.4306 mL
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