Description：

SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.

Chemical Information：

Molecular Weight (MW)		527.04
Formula		C18H15ClN6OS2.CH4O3S
CAS No.		1146618-41-8
Solubility (25°C) *	DMSO	105 mg/mL (199.22 mM)
	Water	6 mg/mL (11.38 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8974 mL	9.4869 mL	18.9739 mL
5 mM	0.3795 mL	1.8974 mL	3.7948 mL
10 mM	0.1897 mL	0.9487 mL	1.8974 mL
50 mM	0.0379 mL	0.1897 mL	0.3795 mL

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