Description：

SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. Phase 1.

Chemical Information：

Molecular Weight (MW)		380.53
Formula		C17H24N4O2S2
CAS No.		345627-80-7
Solubility (25°C) *	DMSO	76 mg/mL (199.72 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6279 mL	13.1396 mL	26.2791 mL
5 mM	0.5256 mL	2.6279 mL	5.2558 mL
10 mM	0.2628 mL	1.3140 mL	2.6279 mL
50 mM	0.0526 mL	0.2628 mL	0.5256 mL

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