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Description:
SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.
Chemical Information:
Molecular Weight (MW) 273.23 Formula
C11H6F3NO2S
CAS No. 438190-29-5 Solubility (25°C) * DMSO 55 mg/mL (201.29 mM) Water Insoluble Alcohol 32 mg/mL (117.11 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.6599 mL 18.2996 mL 36.5992 mL 5 mM 0.7320 mL 3.6599 mL 7.3198 mL 10 mM 0.3660 mL 1.8300 mL 3.6599 mL 50 mM 0.0732 mL 0.3660 mL 0.7320 mL
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