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Description:
SKI II is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.
Chemical Information:
Molecular Weight (MW) 302.78 Formula
C15H11ClN2OS
CAS No. 312636-16-1 Solubility (25°C) * DMSO 61 mg/mL (201.46 mM) Water Insoluble Alcohol 61 mg/mL (201.46 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.3027 mL 16.5136 mL 33.0273 mL 5 mM 0.6605 mL 3.3027 mL 6.6055 mL 10 mM 0.3303 mL 1.6514 mL 3.3027 mL 50 mM 0.0661 mL 0.3303 mL 0.6605 mL
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