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AZ5104

AZ5104

Catalog Number: CC7454 Rank: comment rank 5

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$ 277.00
$ 557.00
$ 95.00
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Description:

AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nm, 6 1 and 25 nm for egfr (l858r>
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Chemical Information:

Molecular Weight (MW) 485.58
Formula

 

C27H31N7O2

 

CAS No. 1421373-98-9
Solubility (25°C) * DMSO 97 mg/mL (199.76 mM)
Water Insoluble
Alcohol 23 mg/mL warmed (47.36 mM)


Biological Activity:

Targets
IC50
ROCK
~0.5 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0594 mL 10.2970 mL 20.5939 mL
5 mM 0.4119 mL 2.0594 mL 4.1188 mL
10 mM 0.2059 mL 1.0297 mL 2.0594 mL
50 mM 0.0412 mL 0.2059 mL 0.4119 mL


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