Description：

AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.

Chemical Information：

Molecular Weight (MW)		412.51
Formula		C21H24N4O3S
CAS No.		1233339-22-4
Solubility (25°C) *	DMSO	83 mg/mL (201.2 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (7.27 mM)

Biological Activity：

Targets IC50

p38β MAPK p38α MAPK 220 nM 10 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4242 mL	12.1209 mL	24.2418 mL
5 mM	0.4848 mL	2.4242 mL	4.8484 mL
10 mM	0.2424 mL	1.2121 mL	2.4242 mL
50 mM	0.0485 mL	0.2424 mL	0.4848 mL

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