Description：

SHP099 is a highly potent, selective and orally bioavailable small-molecule SHP2 inhibitor with an IC50 value of 0.071 μM and shows no activity against SHP1.

Chemical Information：

Molecular Weight (MW)		425.18
Formula		C16H21Cl4N5
CAS No.		1801747-42-1(free base)
Solubility (25°C) *	DMSO	2 mg/mL warmed (4.7 mM)
	Water	77 mg/mL warmed (181.09 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3519 mL	11.7597 mL	23.5195 mL
5 mM	0.4704 mL	2.3519 mL	4.7039 mL
10 mM	0.2352 mL	1.1760 mL	2.3519 mL
50 mM	0.0470 mL	0.2352 mL	0.4704 mL

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