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SGX-523

SGX-523

Catalog Number: CC1268 Rank: comment rank 5

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Description:

SGX-523 is a selective Met inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-Raf, Abl and p38α. Phase 1.

Chemical Information:

Molecular Weight (MW) 359.41
Formula

 

C18H13N7S

 

CAS No. 1022150-57-7
Solubility (25°C) * DMSO 3 mg/mL warmed (8.34 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.7823 mL 13.9117 mL 27.8234 mL
5 mM 0.5565 mL 2.7823 mL 5.5647 mL
10 mM 0.2782 mL 1.3912 mL 2.7823 mL
50 mM 0.0556 mL 0.2782 mL 0.5565 mL


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