Description：

SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.

Chemical Information：

Molecular Weight (MW)		405.42
Formula		C20H22F3N5O
CAS No.		1025065-69-3
Solubility (25°C) *	DMSO	81 mg/mL (199.79 mM)
	Water	Insoluble
	Alcohol	81 mg/mL (199.79 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4666 mL	12.3329 mL	24.6658 mL
5 mM	0.4933 mL	2.4666 mL	4.9332 mL
10 mM	0.2467 mL	1.2333 mL	2.4666 mL
50 mM	0.0493 mL	0.2467 mL	0.4933 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last