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Description:
SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively.
Chemical Information:
Molecular Weight (MW) 509.04 Formula
C28H33ClN4O3
CAS No. 1613695-14-9 Solubility (25°C) * DMSO 100 mg/mL (196.44 mM) Water Insoluble Alcohol 100 mg/mL (196.44 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9645 mL 9.8224 mL 19.6448 mL 5 mM 0.3929 mL 1.9645 mL 3.9290 mL 10 mM 0.1964 mL 0.9822 mL 1.9645 mL 50 mM 0.0393 mL 0.1964 mL 0.3929 mL
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