Description：

SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.

Chemical Information：

Molecular Weight (MW)		618.57
Formula		C28H40BrN7O4
CAS No.		1561178-17-3
Solubility (25°C) *	DMSO	100 mg/mL (161.66 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (161.66 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6166 mL	8.0832 mL	16.1663 mL
5 mM	0.3233 mL	1.6166 mL	3.2333 mL
10 mM	0.1617 mL	0.8083 mL	1.6166 mL
50 mM	0.0323 mL	0.1617 mL	0.3233 mL

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