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Description:
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3.
Chemical Information:
Molecular Weight (MW) 354.36 Formula
C18H16F2N6
CAS No. 905586-69-8 Solubility (25°C) * DMSO 71 mg/mL (200.36 mM) Water Insoluble Alcohol 3 mg/mL (8.46 mM)
Biological Activity:
Targets IC50
Endothelin A (ET 21 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.8220 mL 14.1099 mL 28.2199 mL 5 mM 0.5644 mL 2.8220 mL 5.6440 mL 10 mM 0.2822 mL 1.4110 mL 2.8220 mL 50 mM 0.0564 mL 0.2822 mL 0.5644 mL
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