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Description:
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
Chemical Information:
Molecular Weight (MW) 238.28 Formula
C15H14N2O
CAS No. 194413-58-6 Solubility (25°C) * DMSO 22 mg/mL (92.32 mM) Water Insoluble Alcohol 2 mg/mL (8.39 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 4.1967 mL 20.9837 mL 41.9674 mL 5 mM 0.8393 mL 4.1967 mL 8.3935 mL 10 mM 0.4197 mL 2.0984 mL 4.1967 mL 50 mM 0.0839 mL 0.4197 mL 0.8393 mL
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