Description：

Selisistat (EX 527) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.

Chemical Information：

Molecular Weight (MW)		248.71
Formula		C13H13ClN2O
CAS No.		49843-98-3
Solubility (25°C) *	DMSO	49 mg/mL (197.01 mM)
	Water	Insoluble
	Alcohol	18 mg/mL (72.37 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	4.0207 mL	20.1037 mL	40.2075 mL
5 mM	0.8041 mL	4.0207 mL	8.0415 mL
10 mM	0.4021 mL	2.0104 mL	4.0207 mL
50 mM	0.0804 mL	0.4021 mL	0.8041 mL

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