Description：

Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.

Chemical Information：

Molecular Weight (MW)		501.72
Formula		C29H43NO4S
CAS No.		166518-60-1
Solubility (25°C) *	DMSO	100 mg/mL (199.31 mM)
	Water	Insoluble
	Alcohol	8 mg/mL (15.94 mM)

Biological Activity：

Targets IC50

Aurora C Aurora B Aurora A 0.432 μM 3.4 μM 3.4 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9931 mL	9.9657 mL	19.9314 mL
5 mM	0.3986 mL	1.9931 mL	3.9863 mL
10 mM	0.1993 mL	0.9966 mL	1.9931 mL
50 mM	0.0399 mL	0.1993 mL	0.3986 mL

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