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Description:
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Phase 2/3.
Chemical Information:
Molecular Weight (MW) 542.03 Formula
C27H32ClN5O5
CAS No. 379231-04-6 Solubility (25°C) * DMSO 35 mg/mL warmed (64.57 mM) Water Insoluble Alcohol 31 mg/mL (57.19 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.8449 mL 9.2246 mL 18.4492 mL 5 mM 0.3690 mL 1.8449 mL 3.6898 mL 10 mM 0.1845 mL 0.9225 mL 1.8449 mL 50 mM 0.0369 mL 0.1845 mL 0.3690 mL
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