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Description:
SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.
Chemical Information:
Molecular Weight (MW) 373.49 Formula
C23H27N5
CAS No. 304909-07-7 Solubility (25°C) * DMSO 21 mg/mL (56.22 mM) Water Insoluble Alcohol 20 mg/mL (53.54 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.6774 mL 13.3872 mL 26.7745 mL 5 mM 0.5355 mL 2.6774 mL 5.3549 mL 10 mM 0.2677 mL 1.3387 mL 2.6774 mL 50 mM 0.0535 mL 0.2677 mL 0.5355 mL
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