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Description:
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
Chemical Information:
Molecular Weight (MW) 275.34 Formula
C16H21NO3
CAS No. 85416-73-5 Solubility (25°C) * DMSO 55 mg/mL (199.75 mM) Water Insoluble Alcohol 55 mg/mL (199.75 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.6319 mL 18.1594 mL 36.3187 mL 5 mM 0.7264 mL 3.6319 mL 7.2637 mL 10 mM 0.3632 mL 1.8159 mL 3.6319 mL 50 mM 0.0726 mL 0.3632 mL 0.7264 mL
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