Description：

(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.

Chemical Information：

Molecular Weight (MW)		450.34
Formula		C21H22Cl2FN5O
CAS No.		1374356-45-2
Solubility (25°C) *	DMSO	42 mg/mL warmed (93.26 mM)
	Water	Insoluble
	Alcohol	22 mg/mL (48.85 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2205 mL	11.1027 mL	22.2054 mL
5 mM	0.4441 mL	2.2205 mL	4.4411 mL
10 mM	0.2221 mL	1.1103 mL	2.2205 mL
50 mM	0.0444 mL	0.2221 mL	0.4441 mL

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