Description：

AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway.

Chemical Information：

Molecular Weight (MW)		3261.55
Formula		C142H226N40O48
CAS No.		1353563-85-5
Solubility (25°C) *	DMSO
	Water	100 mg/mL (30.66 mM)
	Alcohol

Biological Activity：

Targets IC50

PI3Kγ PI3Kδ PI3Kβ PI3Kα 8 nM 300 nM 270 nM 60 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	0.3066 mL	1.5330 mL	3.0660 mL
5 mM	0.0613 mL	0.3066 mL	0.6132 mL
10 mM	0.0307 mL	0.1533 mL	0.3066 mL
50 mM	0.0061 mL	0.0307 mL	0.0613 mL

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