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Rucaparib (AG-014699,PF-01367338) phosphate

Rucaparib (AG-014699,PF-01367338) phosphate

Catalog Number: CC1254 Rank: comment rank 5

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Description:

Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.

Chemical Information:

Molecular Weight (MW) 421.36
Formula

 

C19H18FN3O.H3PO4

 

CAS No. 459868-92-9
Solubility (25°C) * DMSO 84 mg/mL (199.35 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3733 mL 11.8663 mL 23.7327 mL
5 mM 0.4747 mL 2.3733 mL 4.7465 mL
10 mM 0.2373 mL 1.1866 mL 2.3733 mL
50 mM 0.0475 mL 0.2373 mL 0.4747 mL


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