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Description:
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.
Chemical Information:
Molecular Weight (MW) 421.36 Formula
C19H18FN3O.H3PO4
CAS No. 459868-92-9 Solubility (25°C) * DMSO 84 mg/mL (199.35 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3733 mL 11.8663 mL 23.7327 mL 5 mM 0.4747 mL 2.3733 mL 4.7465 mL 10 mM 0.2373 mL 1.1866 mL 2.3733 mL 50 mM 0.0475 mL 0.2373 mL 0.4747 mL
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