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RSL3

RSL3

Catalog Number: CC8311 Rank: comment rank 5

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Description:

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.

Chemical Information:

Molecular Weight (MW) 440.88
Formula

 

C23H21ClN2O5

 

CAS No. 1219810-16-8
Solubility (25°C) * DMSO 88 mg/mL (199.6 mM)
Water Insoluble
Alcohol 22 mg/mL (49.9 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2682 mL 11.3410 mL 22.6819 mL
5 mM 0.4536 mL 2.2682 mL 4.5364 mL
10 mM 0.2268 mL 1.1341 mL 2.2682 mL
50 mM 0.0454 mL 0.2268 mL 0.4536 mL


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