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Description:
Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action.
Chemical Information:
Molecular Weight (MW) 357.43 Formula
C18H19N3O3S
CAS No. 122320-73-4 Solubility (25°C) * DMSO 71 mg/mL (198.64 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.7978 mL 13.9888 mL 27.9775 mL 5 mM 0.5596 mL 2.7978 mL 5.5955 mL 10 mM 0.2798 mL 1.3989 mL 2.7978 mL 50 mM 0.0560 mL 0.2798 mL 0.5596 mL
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