Description：

Roscovitine (Seliciclib, CYC202) is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.

Chemical Information：

Molecular Weight (MW)		354.45
Formula		C19H26N6O
CAS No.		186692-46-6
Solubility (25°C) *	DMSO	71 mg/mL (200.31 mM)
	Water	Insoluble
	Alcohol	6 mg/mL (16.92 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8213 mL	14.1064 mL	28.2127 mL
5 mM	0.5643 mL	2.8213 mL	5.6425 mL
10 mM	0.2821 mL	1.4106 mL	2.8213 mL
50 mM	0.0564 mL	0.2821 mL	0.5643 mL

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